PICO Genesis FX is an advanced fractional picosecond laser treatment performed on the Cutera enlighten platform. It works by delivering ultra-short pulses of laser energy that create controlled micro-injuries in the skin (known as fractionated energy). These micro-injuries trigger your body’s natural healing process, stimulating collagen and elastin production to remodel the dermis and improve skin quality. Unlike traditional lasers that generate significant heat, PICO Genesis FX minimizes thermal damage, making it safer for different skin types while still addressing acne scars, fine lines, and textural irregularities.

While both treatments use the picosecond laser platform, their goals are different. PICO Genesis is primarily designed for pigment correction and skin tone improvement. It uses a multi-pass, non-fractional approach to reduce unwanted pigmentation, sun spots, and uneven skin tone. On the other hand, PICO Genesis FX introduces a fractional mode, which penetrates deeper to specifically target texture issues, acne scars, fine lines, and wrinkles. In short: PICO Genesis = tone and pigment, while PICO Genesis FX = texture, scars, and wrinkles. Many patients combine both for a more comprehensive skin rejuvenation plan.

PICO Genesis FX is highly versatile and can address a wide range of concerns, including:

• Acne scars and post-inflammatory textural changes
• Fine lines and wrinkles caused by aging
• Enlarged pores and uneven skin texture
• Sun damage and photoaging
• Skin laxity and collagen loss
• Certain pigment irregularities as part of an overall revitalization plan

Because it stimulates collagen remodeling, results are natural-looking, long-lasting, and improve over time.

Most patients need a series of 3–4 sessions spaced 4–6 weeks apart for best results. You may begin noticing skin improvements such as smoother texture and a refreshed glow within a few weeks after your first session. However, the most dramatic results typically appear around 3 months after the final treatment as new collagen develops. Your provider will customize the treatment plan depending on the severity of your concerns and your goals.

PICO Genesis FX is considered a low-downtime procedure. After treatment, you may experience temporary redness, swelling, or a mild sunburn-like sensation that usually resolves within 24–48 hours. Most patients are comfortable returning to work or daily activities the next day. Aftercare includes:

• Using gentle, hydrating skincare products
• Avoiding hot showers, saunas, or strenuous exercise for 24 hours
• Applying broad-spectrum SPF daily to protect the healing skin
• Avoiding direct sun exposure while the skin is recovering

Following these steps ensures faster healing and longer-lasting results.

Yes, PICO Genesis FX is generally safe for a wide range of skin tones and types, including darker complexions, because the picosecond technology delivers energy in ultra-short pulses that minimize heat buildup. This reduces the risk of burns or pigmentary complications compared to older laser technologies. That said, your provider will carefully assess your skin type, history of hyperpigmentation, and overall skin health to tailor the settings for maximum safety and effectiveness.

Most patients describe the sensation of PICO Genesis FX as a quick snapping or tingling feeling on the skin. It is generally well-tolerated, and discomfort is minimal. For added comfort, a topical numbing cream can be applied before treatment, especially for more sensitive areas. The procedure is fast, with sessions typically lasting 15–30 minutes depending on the treatment area.

PICO Genesis FX may be used as part of a multi-modal treatment plan for melasma, but expectations must be realistic. Melasma is a chronic, relapsing condition that is very sensitive to sun exposure and hormones. Fractional picosecond treatments can improve pigmentation but must be performed conservatively to reduce the risk of rebound hyperpigmentation. Strict sun protection, ongoing maintenance treatments, and the possible addition of topical brightening agents are recommended for long-term management.