6 Key Benefits Of Adding Benev Exosomes To RF Microneedling

6 Key Benefits of Adding Benev Exosomes to Your Secret Pro RF Microneedling Session

Rf Microneedling Benev Exosomes

Level up your Secret PRO RF Microneedling with Benev Exosomes

Microneedling has long been celebrated in the skincare industry for its effectiveness in rejuvenating the skin and addressing a range of concerns, including wrinkles, scars, and skin laxity. Secret PRO RF Microneedling, an award-winning technology from Cutera, further enhances these benefits by incorporating advanced radiofrequency technology. 

By integrating Benev exosomes into this treatment, the results can be significantly elevated. This blog post will explore six distinct benefits of adding Benev exosomes to the Secret PRO, which itself has garnered numerous accolades for its innovative approach to skincare. These benefits highlight how this combination can deliver superior outcomes, making it a standout option in advanced skin rejuvenation.


What are Benev Exosomes?

Benev exosomes are a cutting-edge product developed through a partnership between BENEV Inc. and ExoCobio. These exosomes are essentially small extracellular vesicles (sEVs) derived from adipose mesenchymal stem cells (ADSC-sEVs). Research involving these exosomes has shown promising results in anti-aging and regenerative therapies.

Benev exosomes distinguish themselves markedly from other exosome products in the market. While many exosome products lack substantial validation, such as clinical research, proof of concept, or transparent ingredient documentation, Benev exosomes are supported by a more robust foundation. Unlike these competitors, Benev provides comprehensive information and verification of its product’s efficacy and safety. 

This includes adherence to Good Manufacturing Practices (GMP), which ensures the highest standard in production, and extensive clinical research to back its claims. 

The lack of documentation and clinical backing in many other exosome products raises concerns about their reliability and effectiveness. Therefore, Benev exosomes stand out as a reputable choice for those seeking scientifically proven and safely manufactured solutions for skin rejuvenation.


Why Benev Exosomes Stand Out

Benev exosomes represent a forefront of scientific achievement in the field of regenerative medicine, distinguished by their extensive development and proven effectiveness. Here’s what sets Benev exosomes apart:

  1. Extensive Research & Development: More than $80 million has been invested in research and development, highlighting the commitment to creating a robust and effective product.
  2. Scientific Validation: The efficacy and safety of Benev exosomes are supported by over 25 clinical publications, ensuring they are backed by solid scientific evidence.
  3. Innovative Patents: Benev has secured more than 56 global patents, demonstrating its leadership in developing unique and effective exosomal technologies.
  4. Global Recognition: Benev is recognized as the 4th largest Exosome Research Company worldwide, reflecting its significant impact and authority in the field.
  5. Leading Facility: Benev operates the largest global GMP (Good Manufacturing Practices) facility dedicated to exosome production, ensuring high standards of quality and safety.
  6. Global Impact: Benev exosomes have been used in over 1 million cases globally, underscoring their widespread acceptance and effectiveness across different applications.
Here’s why you should consider incorporating Benev exosomes into your next Secret Pro RF Microneedling session:

1. Enhanced Cellular Communication

Benev exosomes are densely packed with growth factors, peptides, and RNA, which play a crucial role in facilitating efficient communication between cells. When these exosomes are used alongside Secret Pro RF Microneedling, they significantly enhance the natural signaling mechanisms that promote skin healing and regeneration. This improved cellular dialogue ensures that signals for repair and rejuvenation are more effectively relayed and executed within the skin’s structure.

Why it Matters 

Enhanced cellular communication is vital as it directly influences the speed and efficiency of the skin’s regeneration process. By optimizing the way cells interact and respond to damage, Benev exosomes can accelerate the healing process, leading to quicker recovery and more rapid rejuvenation.

 This results in more effective treatment outcomes, with noticeable improvements in skin appearance and health in a shorter timeframe. This is especially beneficial for those seeking swift results from their skincare treatments, allowing them to enjoy rejuvenated, vibrant skin with minimal downtime.


2. Boosted Collagen Production

The combination of RF energy and microneedling already promotes collagen production. By integrating Benev exosomes into this regimen, the effects on collagen synthesis are notably amplified. Benev exosomes are rich in concentrated growth factors that specifically focus on skin renewal and rejuvenation. 

These growth factors target the cellular processes that enhance skin texture and elasticity, making this combination particularly effective for achieving youthful, revitalized skin. The synergy of RF energy, microneedling, and exosomes creates an environment conducive to robust skin regeneration, offering a more pronounced and sustainable improvement in skin health and appearance.

Why it Matters

 In a recent prospective and split-faced study, microneedling was utilized to enhance the absorption of exosomes into the skin (Park et al., 2023). The study found greater clinical improvements in skin wrinkles, elasticity, hydration, and pigmentation were observed on the side treated with HACS compared to the control side. Histopathological evaluations further supported these findings. The study concluded that combined treatment using exosomes and microneedling is effective and safe for treating facial skin aging.


Benev Exosomes Face Before & After

3. Improved Skin Texture and Tone

Benev exosomes are pivotal in refining skin texture and evening out skin tone. They promote the growth of new, healthy cells while facilitating the natural shedding of older, damaged cells. This cellular renewal is crucial for rejuvenating the skin’s surface, making it smoother and more uniform.

Why It Matters

 Enhanced skin texture and tone mean that you can achieve a more polished appearance with visibly fewer imperfections such as scars, rough patches, and color inconsistencies. The result is smoother, more radiant skin that looks visibly refreshed and revitalized. This improvement not only enhances aesthetic appeal but can also boost confidence and satisfaction with one’s appearance. The ability of Benev exosomes to effectively renew and restore the skin makes them an essential component of advanced skincare, providing noticeable benefits that help maintain a youthful and healthy complexion.

4. Reduced Recovery Time

The incorporation of exosomes in treatments like Secret Pro RF Microneedling leverages their potent anti-inflammatory properties, significantly reducing post-treatment redness and swelling. Exosomes aid in calming the skin and facilitating a quicker healing process by minimizing inflammatory responses, which are common after microneedling procedures.

Why It Matters

This reduction in recovery time is a crucial benefit as it allows for a smoother and faster healing process following a Secret Pro RF Microneedling session. Clients can experience less downtime, which means they can resume their daily activities much sooner without the extended periods of skin sensitivity or visible irritation that typically follow intensive skin treatments. This convenience is especially beneficial for those with busy schedules, making advanced skincare solutions more accessible and less disruptive to everyday life.


5. Enhanced Skin Brightening

Benev exosomes contain bioactive molecules that help lighten the skin by reducing melanin production, as demonstrated in clinical studies.

Why it Matters

This leads to a brighter and more even complexion, adding an aesthetic boost to the rejuvenative effects of microneedling. A research study evaluated the effectiveness of an ASC-exosome-containing formulation through a prospective, split-face, double-blind, randomized placebo-controlled design to determine its skin-brightening capabilities (Cho et al., 2020). Results showed that melanin levels started to decrease 2 weeks after initiating treatment, with a statistically significant reduction occurring by the 4th week in the areas treated with the ASC-exosomes compared to the placebo-treated areas.

6. Long-lasting Results

The combined application of RF microneedling and exosomes creates a synergistic effect that not only boosts the initial treatment outcomes but also prolongs the effects. This powerful synergy works by enhancing the skin’s natural regeneration processes, resulting in sustained improvements in skin texture and elasticity.

Why It Matters:

The extended duration of the benefits provided by this combination means that clients can enjoy longer-lasting results, reducing the need for frequent follow-up treatments. This translates into fewer sessions and less overall maintenance, which is both cost-effective and convenient for the client. It allows for more time to enjoy a youthful and rejuvenated appearance without the constant need for retreatment, offering a practical and efficient solution in skincare regimens.



By incorporating Benev exosomes into your Secret Pro RF Microneedling treatment, you can significantly elevate the skin rejuvenation process. This powerful combination is ideal for addressing specific skin concerns or simply enhancing your daily skincare routine to maintain youthful, glowing skin. The integration of Benev exosomes enhances the already profound benefits of RF microneedling, making it a highly effective solution for improving skin texture, tone, and overall health.

Don’t miss out on the opportunity to transform your skin. Schedule your consultation today to learn more about how Secret Pro RF Microneedling with Benev exosomes can revitalize your appearance and help you achieve the radiant, healthy skin you deserve.



Cho, B. S., Lee, J., Won, Y., Duncan, D. I., Jin, R. C., Lee, J., Kwon, H. H., Park, G.-H., Yang, S. H., & Park, B. C. (2020). Skin brightening efficacy of exosomes derived from human adipose tissue-derived stem/stromal cells: A prospective, split-face, randomized placebo-controlled study. Cosmetics, 7(4), 90.

Park, G., Kwon, H. H., Seok, J., Yang, S. H., Lee, J., Park, B. C., Shin, E., & Park, K. Y. (2023). Efficacy of combined treatment with human adipose tissue stem cell‐derived exosome‐containing solution and microneedling for facial skin aging: A 12‐week prospective, randomized, split‐face study. Journal of Cosmetic Dermatology, 22(12), 3418–3426.


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